Zymosan—Induced Arthritis

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چکیده

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The effect of interleukin 17 and Toll-like receptor 2 on CD11b expression and apoptosis of neutrophils in zymosaninduced arthritis and paw oedema

We investigated the effect of interleukin (IL)-17 on Ly6G(+) cell apoptosis in zymosan-induced arthritis (ZIA) and oedema (ZIO). Zymosan injection at the ankle joint caused swelling and coincided with histological joint alterations and IL-17A expression in areas with cell infiltrates. Flow cytometry of blood demonstrated increased frequencies of Ly6G(+)CD11b(+) cells and their decreased apoptos...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 1977

ISSN: 0004-3591,1529-0131

DOI: 10.1002/art.1780200714